Conditions / Genetic
familial partial lipodystrophy type 3
info · Genetic
A familial partial lipodystrophy characterized by autosomal dominant inheritance that has_material_basis_in mutation in the PPARG gene on chromosome 3p25.
Signs and symptoms
- Insulin resistance
- Lipodystrophy
- Hypertriglyceridemia
- Hypertension
- Type II diabetes mellitus
- Hyperinsulinemia
- Decreased circulating HDL-C concentration
- Hyperglycemia
- Hepatic steatosis
- Cirrhosis
Also known as: FPLD3; PPARG-related FPLD; PPARG-related familial partial lipodystrophy; familial partial lipodystrophy associated with PPARG mutations