Conditions / Skin
familial progressive hyperpigmentation with or without hypopigmentation
info · Skin
A skin disease characterized by progressive, diffuse hyperpigmentation of variable intensity sometimes associated with cafe-au-lait macules and larger hypopigmented ash-leaf macules that has_material_basis_in heterozygous mutation in the KITLG gene on chromoso
A skin disease characterized by progressive, diffuse hyperpigmentation of variable intensity sometimes associated with cafe-au-lait macules and larger hypopigmented ash-leaf macules that has_material_basis_in heterozygous mutation in the KITLG gene on chromosome 12q21.32.
Signs and symptoms
- Hypermelanotic macule
- Progressive hyperpigmentation
- Multiple lentigines
- Cafe-au-lait spot
- Hypopigmented skin patches
- Hyperkeratosis
- Vitiligo
Also known as: FPHH; MUH; melanosis universalis hereditaria