Conditions / Genetic
focal or diffuse nonepidermolytic palmoplantar keratoderma
info · Genetic
A nonepidermolytic palmoplantar keratoderma characterized by focal or diffuse palmoplantar keratodermas with minor or absent nail changes that has_material_basis_in heterozygous mutation in the KRT6C gene on chromosome 12q13.13.
Signs and symptoms
- Epidermal acanthosis
- Plantar hyperkeratosis
- Palmoplantar keratoderma
- Oral leukoplakia
Also known as: PPKNEFD; autosomal dominant focal non-epidermolytic palmoplantar keratoderma with plantar blistering