Conditions / Nervous system
frontotemporal dementia and/or amyotrophic lateral sclerosis 4
info · Nervous system
An amyotrophic lateral sclerosis that has_material_basis_in mutation in the TBK1 gene on chromosome 12q14.
Signs and symptoms
- Abnormal lower motor neuron morphology
- Hyporeflexia
- Mutism
- Skeletal muscle atrophy
- Dysphagia
- Language impairment
- Frontotemporal dementia
- Bulbar palsy
- Cerebral cortical atrophy
- Dysarthria
Also known as: FTDALS4