gelatinous drop-like corneal dystrophy

An epithelial and subepithelial dystrophy that is characterized by severe corneal amyloidosis leading to blindness and that has_material_basis_in homozygous or compound heterozygous mutation in the TACSTD2 gene which encodes the monoclonal antibody-defined, tu

An epithelial and subepithelial dystrophy that is characterized by severe corneal amyloidosis leading to blindness and that has_material_basis_in homozygous or compound heterozygous mutation in the TACSTD2 gene which encodes the monoclonal antibody-defined, tumor-associated antigen GA733-1, on chromosome 1p32.

Signs and symptoms

• Corneal foreign body sensation
• Corneal dystrophy
• Photophobia
• Reduced visual acuity
• Visual impairment
• Blurred vision

Also known as: GDCD; corneal amyloidosis; primary familial amyloidosis of the cornea; subepithelial amyloidosis of the cornea