Conditions / Syndrome
HELIX syndrome
info · Syndrome · ICD-10: N25.8
A syndrome characterized by hypohidrosis, electrolyte imbalance, lacrimal gland dysfunction, ichthyosis, and xerostomia that has_material_basis_in homozygous mutation in the CLDN10 gene on chromosome 13q32.
Signs and symptoms
- Anhidrosis
- Hypermagnesemia
- Xerostomia
- Hyperparathyroidism
- Alacrima
- Heat intolerance
- Renal insufficiency
- Dry skin
- Polydipsia
- Hypokalemia
Also known as: hypohidrosis, electrolyte imbalance, lacrimal gland dysfunction, ichthyosis, and xerostomia