hemophilia B

A hemophilia that has_material_basis_in Factor IX deficiency, which makes coagulation much more prolonged. The disease is inherited as an X-linked recessive trait.

Signs and symptoms

• Reduced factor IX activity
• Bruising susceptibility
• Persistent bleeding after trauma
• Joint hemorrhage
• Prolonged whole-blood clotting time
• Osteoarthritis
• Gastrointestinal hemorrhage
• Prolonged partial thromboplastin time
• Epistaxis
• Melena

Medications that may treat it

anti-inhibitor coagulant complex danaparoid dicumarol etranacogene dezaparvovec factor IX factor VII fidanacogene elaparvovec fitusiran marstacimab phenprocoumon warfarin

Also known as: Congenital factor IX deficiency; Congenital factor IX disorder; deficiency, functional factor IX; factor IX deficiency