hereditary diffuse gastric cancer

info · Genetic

A diffuse gastric cancer that is characterized by characterized by the development of diffuse (signet ring cell) gastric cancer at a young age, associated with germline heterozygous mutations of CDH1, MAP3K6 and CTNNA1 genes.

Signs and symptoms

Stomach cancer
Atrophic gastritis
Cleft palate
Cleft upper lip