Conditions / Genetic

hereditary spastic paraplegia 14

info · Genetic · ICD-10: G11.4

A hereditary spastic paraplegia that has_material_basis_in variation in the chromosome region 3q27-q28.

Signs and symptoms

  • Mild intellectual disability
  • Pes cavus
  • Babinski sign
  • Lower limb muscle weakness
  • Spastic gait
  • Lower limb spasticity
  • Motor axonal neuropathy
  • Spastic paraplegia
  • Hyperreflexia

Also known as: SPG14; autosomal recessive spastic paraplegia 14; autosomal recessive spastic paraplegia type 14