Conditions / Genetic

hereditary spastic paraplegia 16

info · Genetic · ICD-10: G11.4

A hereditary spastic paraplegia that has_material_basis_in variation in the chromosome region Xq11.2.

Signs and symptoms

  • Tetraplegia
  • Facial hypotonia
  • Strabismus
  • Urinary urgency
  • Babinski sign
  • Shuffling gait
  • Urinary incontinence
  • Lower limb spasticity
  • Lower limb muscle weakness
  • Urinary bladder sphincter dysfunction

Also known as: SPG16; X-linked spastic paraplegia 16; X-linked spastic paraplegia type 16