Conditions / Genetic
hereditary spastic paraplegia 31
info · Genetic · ICD-10: G11.4
A hereditary spastic paraplegia that has_material_basis_in mutation in the REEP1 gene on chromosome 2p11.
Signs and symptoms
- Babinski sign
- Spastic gait
- Lower limb muscle weakness
- Skeletal muscle atrophy
- Dysarthria
- Lower limb spasticity
- Ankle clonus
- Spastic paraplegia
- Hyperreflexia
- Dysphagia
Also known as: SPG31; autosomal dominant spastic paraplegia 31; autosomal dominant spastic paraplegia type 31