Conditions / Genetic

hereditary spastic paraplegia 32

info · Genetic · ICD-10: G11.4

A hereditary spastic paraplegia that has_material_basis_in variation in the chromosome region 14q12-q21.

Signs and symptoms

  • Cerebral atrophy
  • Mild intellectual disability
  • Pes cavus
  • Gait disturbance
  • Babinski sign
  • Hypoplasia of the corpus callosum
  • Cerebellar atrophy
  • Spastic gait
  • Lower limb spasticity
  • Ankle clonus

Also known as: SPG32; autosomal recessive spastic paraplegia 32; autosomal recessive spastic paraplegia type 32