Conditions / Genetic
hereditary spastic paraplegia 33
info · Genetic
A hereditary spastic paraplegia that has_material_basis_in mutation in the ZFYVE27 gene on chromosome 10q24.
Signs and symptoms
- Talipes equinovarus
- Babinski sign
- Lower limb muscle weakness
- Spastic gait
- Lower limb spasticity
- Spastic paraplegia
- Ankle clonus
- Hyperreflexia
Also known as: SPG33; autosomal dominant spastic paraplegia 33