Conditions / Genetic
hereditary spastic paraplegia 35
info · Genetic · ICD-10: G11.4
A hereditary spastic paraplegia that has_material_basis_in mutation in the FA2H gene on chromosome 16q23.1.
Signs and symptoms
- Lower limb spasticity
- Gait disturbance
- Dystonia
- Strabismus
- Dysmetria
- Cerebellar atrophy
- Ataxia
- Neurodegeneration
- Nystagmus
- Abnormal periventricular white matter morphology
Also known as: FAHN; SPG35; autosomal recessive spastic paraplegia 35; autosomal recessive spastic paraplegia type 35; fatty acid hydroxylase-associated neurodegeneration