hereditary spastic paraplegia 37

A hereditary spastic paraplegia that has_material_basis_in variation in the chromosome region 8p21.1-q13.3.

Signs and symptoms

• Urinary urgency
• Lower limb hyperreflexia
• Urinary incontinence
• Spastic gait
• Lower limb spasticity
• Spastic paraplegia
• Impaired vibration sensation in the lower limbs
• Babinski sign
• Ankle clonus
• Upper limb hyperreflexia

Also known as: SPG37; autosomal dominant spastic paraplegia 37; autosomal dominant spastic paraplegia type 37