Conditions / Genetic
hereditary spastic paraplegia 57
info · Genetic · ICD-10: G11.4
A hereditary spastic paraplegia that has_material_basis_in mutation in the TFG gene on chromosome 3q12.
Signs and symptoms
- Visual loss
- Babinski sign
- Delayed ability to walk
- Lower limb spasticity
- Hand muscle atrophy
- Demyelinating motor neuropathy
- Lower limb amyotrophy
- Optic atrophy
- Loss of ambulation
- Spastic paraplegia
Also known as: SPG57; autosomal recessive spastic paraplegia 57; autosomal recessive spastic paraplegia type 57