Conditions / Genetic

hereditary spastic paraplegia 61

info · Genetic · ICD-10: G11.4

A hereditary spastic paraplegia that has_material_basis_in mutation in the ARL6IP1 gene on chromosome 16p12.

Signs and symptoms

  • Hyperactive patellar reflex
  • Inability to walk
  • Motor polyneuropathy
  • Scissor gait
  • Sensory neuropathy
  • Spasticity
  • Absent Achilles reflex
  • Spastic paraplegia
  • Intellectual disability

Also known as: SPG61; autosomal recessive spastic paraplegia 61; autosomal recessive spastic paraplegia type 61