Conditions / Genetic
hereditary spastic paraplegia 63
info · Genetic · ICD-10: G11.4
A hereditary spastic paraplegia that has_material_basis_in mutation in the AMPD2 gene on chromosome 1p13.
Signs and symptoms
- Hypertonia
- Delayed ability to walk
- Gait disturbance
- Babinski sign
- Scissor gait
- Abnormal periventricular white matter morphology
- Hyperreflexia
- Skeletal muscle atrophy
- Clonus
- Hypoplasia of the corpus callosum
Also known as: SPG63; autosomal recessive spastic paraplegia 63; spastic paraplegia 63