hereditary spastic paraplegia 73

A hereditary spastic paraplegia that has_material_basis_in mutation in the CPT1C gene on chromosome 19q13.

Signs and symptoms

• Skeletal muscle atrophy
• Babinski sign
• Gait disturbance
• Prolonged central motor conduction time
• Proximal muscle weakness
• Spastic paraplegia
• Impaired distal vibration sensation
• Hyperreflexia
• Claw toe deformity

Also known as: SPG73; autosomal dominant spastic paraplegia 73; autosomal dominant spastic paraplegia type 73