hereditary spastic paraplegia 77

A hereditary spastic paraplegia that has_material_basis_in mutation in the FARS2 gene on chromosome 6p25.

Signs and symptoms

• Lower limb hyperreflexia
• Lower limb muscle weakness
• Spastic paraplegia
• Babinski sign
• Lower limb amyotrophy
• Upper limb muscle weakness

Also known as: SPG77; autosomal recessive spastic paraplegia 77