Conditions / Nervous system

Huntington's disease

info · Nervous system · ICD-10: G10

A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutami

A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities.

Signs and symptoms

  • Bradykinesia
  • Abnormality of eye movement
  • Seizure
  • Cerebellar atrophy
  • Gait ataxia
  • Chorea
  • Gliosis
  • Depression
  • Dementia
  • Neuronal loss in central nervous system

Medications that may treat it

baclofen perphenazine pimozide tetrabenazine ubidecarenone

Also known as: HD; Huntington disease; Huntington's chorea