Conditions / Nervous system

hyperekplexia 3

info · Nervous system · ICD-10: G25.8

A hyperekplexia that has_material_basis_in homozygous or compound heterozygous mutation in the SLC6A5 gene on chromosome 11p15.

Signs and symptoms

  • Exaggerated startle response
  • Hypertonia
  • Muscle stiffness
  • Bilateral tonic-clonic seizure
  • Meconium stained amniotic fluid
  • Hiatus hernia
  • Global developmental delay
  • Gastroesophageal reflux
  • Ventouse delivery
  • Syncope

Also known as: HKPX3