hypertrophic cardiomyopathy 15

A familial hypertrophic cardiomyopathy that has_material_basis_in heterozygous mutation in the vinculin gene (VCL) on chromosome 10q22.

Signs and symptoms

• Myofiber disarray
• Cardiomyocyte hypertrophy
• Hyperdynamic left ventricular ejection fraction
• Apical hypertrophic cardiomyopathy
• Pulmonary arterial hypertension
• Hypertrophic cardiomyopathy
• Congestive heart failure
• Endocardial fibrosis
• Left ventricular outflow tract obstruction
• Exertional dyspnea

Also known as: CMH15; cardiomyopathy familial hypertrophic 15