hypogonadotropic hypogonadism 22 with or without anosmia

A hypogonadotropic hypogonadism that has_material_basis_in homozygous mutation in the FEZF1 gene on chromosome 7q31.

Signs and symptoms

• Micropenis
• Decreased circulating luteinizing hormone level
• Decreased circulating follicle stimulating hormone concentration
• Decreased serum testosterone concentration
• Anosmia
• Decreased serum estradiol
• Decreased testicular size
• Hypogonadism
• Reduced response to gonadotropin-releasing hormone stimulation test
• Cryptorchidism