immunodeficiency 123

info · Immune

A T cell deficiency that is characterized by the onset of HPV-related common cutaneous warts in the first decade of life and that has_material_basis_in homozygous mutation in the CD28 gene on chromosome 2q33.

Signs and symptoms

Persistent EBV viremia
Persistent CMV viremia
Verrucae
Cutaneous horn
Recurrent otitis media
Disseminated cutaneous warts
Unusual molluscum contagiosum
Genital warts
Verruca plana

Also known as: immunodeficiency 123 with HPV-related verrucosis