immunodeficiency 125

info · Immune

A B cell deficiency that is characterized by recurrent diarrhea and failure to thrive beginning in infancy followed by recurrent bacterial, viral, and fungal infections and that has_material_basis_in homozygous mutation in the FLT3LG gene on chromosome 19q13.

Signs and symptoms

Otosclerosis
Hearing impairment
Recurrent lower respiratory tract infections
Bronchial wall thickening
Chronic cough
Intrahepatic bile duct dilatation
Disseminated cutaneous warts
Failure to thrive
Anemia
Recurrent bacterial infections