immunodeficiency 130 with HPV-related verrucosis

A primary immunodeficiency disease that is characterized mainly by the onset of warts and verrucous or plaque-like skin lesions associated with HPV infection, usually in the first 3 decades of life and that has_material_basis_in homozygous mutation in the IL7

A primary immunodeficiency disease that is characterized mainly by the onset of warts and verrucous or plaque-like skin lesions associated with HPV infection, usually in the first 3 decades of life and that has_material_basis_in homozygous mutation in the IL7 gene on chromosome 8q21.

Signs and symptoms

• Decreased total T cell count
• Decreased total lymphocyte count
• Cryptococcal meningitis
• Persistent human papillomavirus infection
• Verrucae
• Squamous cell carcinoma of the skin