Conditions / Immune
immunodeficiency 65
info · Immune
A primary immunodeficiency disease characterized by onset in early infancy of recurrent and severe viral infections, impaired cellular type I interferon response, and poor outcomes after vaccination with live attenuated vaccines that has_material_basis_in homo
A primary immunodeficiency disease characterized by onset in early infancy of recurrent and severe viral infections, impaired cellular type I interferon response, and poor outcomes after vaccination with live attenuated vaccines that has_material_basis_in homozygous or compound heterozygous mutation in the IRF9 gene on chromosome 14q12.
Signs and symptoms
- Gingivitis
- Stomatitis
- Bronchiectasis
- Recurrent gastroenteritis
- Recurrent viral infections
Also known as: IMD65; immunodeficiency 65, susceptibility to viral infections