immunodeficiency 79

A T cell deficiency characterized by childhood onset of recurrent and recalcitrant skin warts due to uncontrolled viral infection with human papillomavirus and absence of the CD4 antigen on T cells, monocytes, and dendritic cells that has_material_basis_in hom

A T cell deficiency characterized by childhood onset of recurrent and recalcitrant skin warts due to uncontrolled viral infection with human papillomavirus and absence of the CD4 antigen on T cells, monocytes, and dendritic cells that has_material_basis_in homozygous or compound heterozygous mutation in CD4 on chromosome 12p13.

Signs and symptoms

• Palmar warts
• Recurrent otitis media
• Plantar warts
• Recurrent upper respiratory tract infections
• Disseminated cutaneous warts
• Decreased total CD4+ T cell proportion

Also known as: IMD79