Conditions / Skin
inflammatory poikiloderma with hair abnormalities and acral keratoses
info · Skin
A skin disease characterized by mottled hyper- and hypopigmentation of the skin, sparse scalp hair and eyelashes, sparse or absent eyebrows, and palmoplantar keratoses that has_material_basis_in homozygous mutation in the LTV1 gene on chromosome 6q24.2.
Signs and symptoms
- Acrokeratosis
- Mottled pigmentation
- Sparse eyelashes
- Poikiloderma
- Absent eyebrow
- Pigment incontinence
- Sparse scalp hair
- Sparse eyebrow
Also known as: IPHAK; LIPHAK; LIPHAK syndrome