intrahepatic cholestasis of pregnancy 1

info · Genetic

An intrahepatic cholestasis of pregnancy characterized by autosomal dominant inheritance that has_material_basis_in mutation in the ATP8B1 gene on chromosome 18q21.

Signs and symptoms

Increased serum bile acid concentration during pregnancy
Abnormal liver function tests during pregnancy
Pruritus
Intrahepatic cholestasis
Fetal distress
Elevated circulating hepatic transaminase concentration
Jaundice
Premature birth