Conditions / Genetic
keratosis palmoplantaris striata 1
info · Genetic
A keratosis palmoplantaris striata that is characterized by hyperkeratotic lesions that are restricted to the pressure regions extending longitudinally in the length of each finger to the palm and that has_material_basis_in heterozygous mutation in the DSG1 ge
A keratosis palmoplantaris striata that is characterized by hyperkeratotic lesions that are restricted to the pressure regions extending longitudinally in the length of each finger to the palm and that has_material_basis_in heterozygous mutation in the DSG1 gene on chromosome 18q12.
Signs and symptoms
- Onycholysis
- Epidermal acanthosis
- Hyperhidrosis
- Orthokeratotic hyperkeratosis
- Yellow nails
- Streaks of hyperkeratosis along each finger onto the palm
- Nail dystrophy
- Palmoplantar hyperkeratosis
- Palmoplantar blistering
- Palmoplantar keratoderma