Conditions / Nervous system

lateral sclerosis

info · Nervous system · ICD-10: G12.23

A motor neuron disease characterized by painless but progressive weakness and stiffness of the muscles of the legs.

Signs and symptoms

  • Dysphagia
  • Spastic dysarthria
  • Babinski sign
  • Spastic tetraparesis
  • Spastic gait
  • Hyperreflexia
  • Abnormal upper motor neuron morphology

Also known as: adult-onset primary lateral sclerosis; primary lateral sclerosis