low molecular weight proteinuria with hypercalciuric nephrocalcinosis

info · Urinary

A Dent disease characterized by elevated levels of low molecular weight proteins in the urine, hypercalciuria, and nephrocalcinosis that has_material_basis_in hemizygous or homozygous mutation in the CLCN5 gene on chromosome Xp11.22.

Signs and symptoms

Nephrocalcinosis
Hyposthenuria
Low-molecular-weight proteinuria
Beta 2-microglobulinuria
Hypercalciuria
Aminoaciduria
Short stature
Renal insufficiency
Focal segmental glomerulosclerosis
Glycosuria