Conditions / Nervous system

Mast syndrome

info · Nervous system · ICD-10: G11.4

A hereditary spastic paraplegia associated with dementia.

Signs and symptoms

  • Hypertonia
  • Cerebellar atrophy
  • Periventricular white matter hyperintensities
  • Thin corpus callosum
  • Hyperreflexia
  • Cerebral atrophy
  • Babinski sign
  • Gait disturbance
  • Dysarthria
  • Dementia

Also known as: SPG21; autosomal recessive spastic paraplegia 21; autosomal recessive spastic paraplegia type 21; hereditary spastic paraplegia 21