Conditions / Syndrome

Meckel syndrome 2

info · Syndrome · ICD-10: Q61.9

A Meckel syndrome that has_material_basis_in an autosomal recessive mutation of the TMEM216 gene on chromosome 11q12.2.

Signs and symptoms

  • Renal cyst
  • Bile duct proliferation
  • Polydactyly
  • Encephalocele
  • Meningocele
  • Cleft palate
  • Postaxial hand polydactyly
  • Bowing of the long bones
  • Intrauterine growth retardation
  • Anencephaly

Also known as: MKS2; Meckel-Gruber syndrome, type 2