Conditions / Syndrome

Meckel syndrome 5

info · Syndrome · ICD-10: Q61.9

A Meckel syndrome that has_material_basis_in an autosomal recessive mutation of the RPGRIP1L gene on chromosome 16q12.2.

Signs and symptoms

  • Cleft palate
  • Anencephaly
  • Postaxial hand polydactyly
  • Bile duct proliferation
  • Occipital encephalocele
  • Renal cyst
  • Microphthalmia
  • Cleft upper lip
  • Bowing of the long bones
  • Postaxial foot polydactyly

Also known as: MKS5; Meckel-Gruber syndrome, type 5