Conditions / Syndrome

Meckel syndrome 8

info · Syndrome · ICD-10: Q61.9

A Meckel syndrome that has_material_basis_in an autosomal recessive mutation of the TCTN2 gene on chromosome 12q24.31.

Signs and symptoms

  • Encephalocele
  • Polydactyly
  • Occipital encephalocele
  • Abdominal distention
  • Polycystic kidney dysplasia
  • Cleft palate
  • Microcephaly
  • Talipes equinovarus
  • Ambiguous genitalia
  • Short nose

Also known as: MKS8; Meckel-Gruber syndrome, type 8