Conditions / Syndrome

Miller-Dieker lissencephaly syndrome

info · Syndrome · ICD-10: Q93.88

A syndrome characterized by classical lissencephaly and distinct facial features and has_material_basis_in submicroscopic deletions of 17p13.3, including the LIS1 gene.

Signs and symptoms

  • Short nose
  • Intellectual disability
  • Lissencephaly
  • Motor delay
  • Thick upper lip vermilion
  • Micrognathia
  • Wide nasal bridge
  • Posteriorly rotated ears
  • Frontal bossing
  • Cavum septum pellucidum

Also known as: MDS; Miller-Dieker syndrome