Moyamoya disease

A cerebral arterial disease characterized by constriction of certain arteries at the base of the brain. Blood flow is blocked by the constriction and also by blood clots.

Signs and symptoms

• Short stature
• Postnatal growth retardation
• Decreased testicular size
• Elevated circulating luteinizing hormone level
• Azoospermia
• Moyamoya phenomenon
• Achalasia
• Hypertension
• Elevated circulating follicle stimulating hormone level
• Stroke-like episode

Also known as: progressive intracranial arterial occlusion