Conditions / Syndrome
multiple endocrine neoplasia type 4
info · Syndrome
A multiple endocrine neoplasia that is characterized by hyperparathyroidism and multiple endocrine tumors and that has_material_basis_in mutations in the CDKN1B gene on chromosome 12p13 resulting in a reduction in the amount of functional p27 tumor suppressor
A multiple endocrine neoplasia that is characterized by hyperparathyroidism and multiple endocrine tumors and that has_material_basis_in mutations in the CDKN1B gene on chromosome 12p13 resulting in a reduction in the amount of functional p27 tumor suppressor protein which allows cells to grow and divide unchecked.
Signs and symptoms
- Primary hyperparathyroidism
- Hypothyroidism
- Hyperparathyroidism
- Hashimoto thyroiditis
- Pancreatic endocrine tumor
- Parathyroid adenoma
- Carcinoma
- Pituitary adenoma
- Carcinoid tumor
- Renal angiomyolipoma
Also known as: Multiple Endocrine Neoplasia, Type IV