myelofibrosis

A myeloid neoplasm that is located in the bone marrow which results in bone marrow being replaced by fibrous (scar) tissue.

Signs and symptoms

• Pallor
• Hepatomegaly
• Extramedullary hematopoiesis
• Splenomegaly
• Purpura
• Fever
• Myeloproliferative disorder
• Hemophagocytosis

Medications that may treat it

busulfan fedratinib momelotinib pacritinib ruxolitinib

Also known as: Agnogenic myeloid metaplasia; Aleukemic myelosis; Megakaryocytic myelosclerosis; bone Marrow Fibrosis; myelosclerosis