nonautoimmune hyperthyroidism

info · Endocrine

A hyperthyroidism that is characterized by passive transfer of maternal autoantibodies and that has_material_basis_in heterozygous mutation in the thyroid-stimulating hormone receptor gene (TSHR) on chromosome 14q31.

Signs and symptoms

Elevated circulating thyroglobulin concentration
Increased circulating T4 concentration
Increased circulating free T3
Hyperthyroidism
Decreased thyroid-stimulating hormone level
Tachycardia
Accelerated skeletal maturation
Hyperactivity
Thyroid hyperplasia
Goiter

Also known as: Congenital nonautoimmune hyperthyroidism