Conditions / Genetic

osteogenesis imperfecta type 12

info · Genetic · ICD-10: Q78.0

An osteogenesis imperfecta that has_material_basis_in mutation in the SP7 gene on chromosome 12q13.

Signs and symptoms

  • Delayed eruption of teeth
  • Short stature
  • Narrow mouth
  • Generalized osteoporosis
  • Motor delay
  • Osteoporosis
  • Prominent forehead
  • Bowing of the legs
  • Recurrent fractures
  • High palate

Also known as: OI12; osteogenesis imperfecta type XII