Conditions / Genetic

osteogenesis imperfecta type 15

info · Genetic · ICD-10: Q78.0

An osteogenesis imperfecta that has_material_basis_in mutation in the WNT1 gene on chromosome 12q13.

Signs and symptoms

  • Bowing of limbs due to multiple fractures
  • Recurrent fractures
  • Blue sclerae
  • Scoliosis
  • Short stature
  • Cerebellar hypoplasia
  • Schizencephaly
  • Hypoplasia of the pons
  • Platyspondyly
  • Thin ribs

Also known as: OI15; osteogenesis imperfecta type XV