Conditions / Syndrome
palmoplantar keratoderma and congenital alopecia 2
info · Syndrome
An ectodermal dysplasia characterized by autosomal recessive inheritance of alopecia, progressive palmoplantar hyperkeratosis resulting in sclerodactyly and usually associated with cataracts and pseudoainhum formation.
Signs and symptoms
- Alopecia totalis
- Facial erythema
- Nail dysplasia
- Camptodactyly of finger
- Sclerodactyly
- Dry skin
- Keratosis pilaris
- Developmental cataract
- Amniotic constriction ring
- Palmoplantar hyperkeratosis
Also known as: CASS; PPK-CA, Wallis type; PPKCA Wallis type; PPKCA2; autosomal recessive palmoplantar hyperkeratosis and congenital alopecia