Conditions / Genetic
Parkinson's disease 1
info · Genetic
A late onset Parkinson's disease that has_material_basis_in mutation in the alpha-synuclein gene on chromosome 4q22.1.
Signs and symptoms
- Bradykinesia
- Rigidity
- Parkinsonism
- Loss of ambulation
- Global brain atrophy
- Resting tremor
- Dystonia
- Shuffling gait
- Sleep disturbance
- Depression
Also known as: autosomal dominant Parkinson disease 1; autosomal dominant Parkinson's disease 1