Conditions / Genetic
Parkinson's disease 23
info · Genetic · ICD-10: G20
An early-onset Parkinson disease that has_material_basis_in homozygous or compound heterozygous mutation in the VPS13C gene on chromosome 15q22.
Signs and symptoms
- Resting tremor
- Rigidity
- Neurofibrillary tangles
- Slurred speech
- Mental deterioration
- Lewy bodies
- Dementia
- Neuronal loss in central nervous system
- Parkinsonism with favorable response to dopaminergic medication
- Loss of ambulation
Also known as: autosomal recessive early-onset Parkinson disease 23; autosomal recessive early-onset Parkinson's disease 23