Conditions / Genetic
Parkinson's disease 8
info · Genetic
A late onset Parkinson's disease that has_material_basis_in heterozygous mutation in the dardarin encoding gene on chromosome 12q12.
Signs and symptoms
- Resting tremor
- Parkinsonism
- Bradykinesia
- Rigidity
- Postural instability
- Substantia nigra gliosis
- Lewy bodies
- Dementia
- Hyposmia
- Parkinsonism with favorable response to dopaminergic medication
Also known as: autosomal dominant Parkinson disease 8; autosomal dominant Parkinson's disease 8