Conditions / Urinary

paroxysmal nocturnal hemoglobinuria

info · Urinary · ICD-10: D59.5, D59.6

An acquired hemolytic anemia that is characterized by abdominal pain, hematuria, esophageal dysmotility and thrombosis, has_material_basis_in defect in the cell membrane glycosyl phosphatidylinositols that protect red blood cells from the innate complement imm

An acquired hemolytic anemia that is characterized by abdominal pain, hematuria, esophageal dysmotility and thrombosis, has_material_basis_in defect in the cell membrane glycosyl phosphatidylinositols that protect red blood cells from the innate complement immune system.

Signs and symptoms

  • Diarrhea
  • Arthralgia
  • Hemolytic anemia
  • Dyspnea
  • Headache
  • Fatigue
  • Abdominal pain

Medications that may treat it

crovalimab eculizumab iptacopan pegcetacoplan ravulizumab